Update on Colorectal Cancer
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Programme
Monday, June 25


09.00 Opening
 
09.20 – 10.30 Diagnostics
Chairs: Paul Fockens, Jaap Stoker  and Niels Wijffels
* Quality assurance in endoscopy - Roland Valori
* Endoscopy – advanced techniques - Brian Saunders
* Imaging for staging of colorectal cancer - Lennart Blomqvist
* Pathology – prognostic markers - Marc v.d. Vijver
* Video lecture (10 min): New endoscopic techniques 

10.30 – 11.00 Coffee break 

11.00 – 12.30 Screening and surveillance
Chairs: Evelien Dekker and Brian Saunders
* Modalities for population screening - Carlo Senore
* Risk profiling - Patrick Bossuyt
* Molecular testing and clinical implications - Gerrit Meijer
* Surveillance of the operated patient  - Evelien Dekker
* Video lecture (10 min): Endoscopy in FAP and Lynch 

12.30 – 13.30 Lunch 

13.30 – 15.00 Controversies in colorectal surgery
Chairs: Willem Bemelman and Eric Rullier
* Endoscopy versus surgery for colorectal adenomas - Paul Fockens
* Tailored approach in abdomino-perineal resection – oncological and reconstructive perspectives - Soren Laurberg
* Smaller holes, bigger surgery - Andre d`Hoore
* Perineal approaches for distal rectal cancer – timing, positioning, extend - Eric Rullier

* Video lecture (10 min): Laparoscopic APR – perineal first in prone position 

15.00 – 15.20 Tea break 

15.20 – 16.50 Metastatic disease
Chairs: Dick Richel and Pieter Tanis
* What to do with the symptomatic and asymptomatic primary tumour in incurable stage IV disease? -  Hans de Wilt 
* Long-term systemic treatment strategies: continuation of therapy vs drug free intervals vs low-dose intervals - Dick Richel 
* Role of targeted agents - Kees Punt
*Timing of multimodality treatment with curative intent in stage IV disease - Pieter Tanis 
* Video lecture (10 min): Synchronous resection primary tumour and metastatic disease
 

Tuesday June 26 

09.00 – 10.30 Genetic susceptibility and basic research
Chairs: Jan Paul Medema, Marc v.d. Vijver and Kristien Tytgat
* Hereditary syndromes with high risk of colorectal cancer - Monique van Leerdam
* Methylation in colorectal cancer -  Manon van Engeland
* Tumour stem cell - Jan Paul Medema
* Microenvironment - Christianne Buskens 

10.30 – 11.00 Coffee break 

11.00 – 12.30 Neo-adjuvant treatment – rectal cancer
Chair: Vincenzo Valentini , Kees Punt
and Debbie Geijsen* 5x5 Gy with short and long interval to surgery - Joachim Widder
* Individualized treatment based on multidisciplinary team discussion - Vincenzo Valentini
* Imaging for response monitoring - Regina Beets-Tan
* Complete response after chemoradiotherapy- no TME surgery necessary? - Eelco de Graaf

12.30 – 13.00 Lunch 

13.30 – 15.00 Controversies
Chairs: Soren Laurberg, Evelien Dekker and Michael Gerhards
* PRO-CON Nationwide FIT-screening - Ernst Kuiper/Carlo Senore
* PRO-CON APR in supine position - Harm Rutten/Torbjörn Holm
* PRO-CON stent as bridge to surgery - Mike Parker/Willem Bemelman 

15.00 – 15.20 Tea break 

15.20 – 16.50 Locoregional recurrence
Chairs: Victor Verwaal, Harm Rutten and Peter Paul Coene
 
* Multimodality treatment of local recurrence in colorectal cancer - Torbjörn Holm
* Animal model of peritoneal carcinomatosis - Ignace de Hingh
* Patient selection and long-term outcome of cytoreduction and HIPEC - Brendon Moran
* Is there an indication for adjuvant HIPEC? - Kurt Van der Speeten 

16.50 Closure  and cocktails

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